3′-Daidzein sulfonate sodium inhibits neuronal apoptosis induced by cerebral ischemia-reperfusion
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چکیده
منابع مشابه
Protective effects of tanshinone IIA sodium sulfonate on ischemia-reperfusion-induced myocardial injury in rats
Objective(s): This study investigated the protective effect of tanshinone IIA sodium sulfonate (TSS) on ischemia-reperfusion (I/R) induced cardiac injury, and the underlying mechanism of action. Materials and Methods:Male Sprague-Dawley rats were subjected to a 30-min coronary arterial occlusion followed by 24 hours' reperfusion. Half an hour before the left coronary artery ligation, rats were ...
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BACKGROUND Calreticulin (CRT) can bind to Fas ligand (FasL) and inhibit Fas/FasL-mediated apoptosis of Jurkat T cells. However, its effect on neuronal cell apoptosis has not been investigated. PURPOSE We aimed to evaluate the neuroprotective effect of CRT following ischemia-reperfusion injury (IRI). METHODS Mice underwent middle cerebral artery occlusion (MCAO) and SH-SY5Y cells subjected t...
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Xanthohumol (XN) is a prenylated chalcone derived from hops (Humuluslupulus L.). Several studies showed that XN exhibited potent neuroprotective activity. However, the precise mechanism and effect of XN in cerebral ischemia/reperfusion (I/R) injury needs further investigations. In the present study, we investigated the role of XN in regulating oxygen-glucose deprivation/reperfusion (OGD/R)-indu...
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Objective(s): Obestatin is a newly discovered peptide with antioxidant activities in different animal models. Recent studies have shown that Obestatin inhibits apoptosis following cardiac ischemia/reperfusion injury. Brain ischemia/reperfusion induces irreversible damage especially in the hippocampus area. This study aimed at examining the protective impact of Obestati...
متن کاملprotective effects of tanshinone iia sodium sulfonate on ischemia-reperfusion-induced myocardial injury in rats
objective(s): this study investigated the protective effect of tanshinone iia sodium sulfonate (tss) on ischemia-reperfusion (i/r) induced cardiac injury, and the underlying mechanism of action. materials and methods:male sprague-dawley rats were subjected to a 30-min coronary arterial occlusion followed by 24 hours' reperfusion. half an hour before the left coronary artery ligation, rats ...
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ژورنال
عنوان ژورنال: International Journal of Molecular Medicine
سال: 2017
ISSN: 1107-3756,1791-244X
DOI: 10.3892/ijmm.2017.2915